Current technology

CERAMENT is a synthetic injectable and flowable bone void filler that consists of a powder component: 40% hydroxyapatite (HA), 60% calcium sulfate (CaS), and a liquid component, which are mixed to form a paste. The proprietary combination of hydroxyapatite and calcium sulfate is designed to enable CERAMENT to resorb at the same rate that bone forms.

Calcium sulfate acts as a resorbable carrier for hydroxyapatite. Hydroxyapatite has a slow resorption rate and high osteoconductivity promoting bone ingrowth and gives long term structural support to the newly formed bone.

CERAMENT G and CERAMENT V have been developed for situations where there is a risk that the bone healing process may be disturbed by the colonization of microbial organisms. The addition of the antibiotics gentamicin in CERAMENT G and vancomycin in CERAMENT V, inhibit colonization by gentamicin or vancomycin-sensitive microorganisms, in order to protect bone healing.

CERAMENT may be used instead of autograft or allograft, and the characteristics of CERAMENT G and V mean that surgeons can manage bone defects in a more patient-friendly single-stage procedure. CERAMENT G has proven clinical outcomes, with one of the lowest (re)fracture and (re)infection rates of any synthetic bone substitute on the market. Moving to a single-stage from a multi-stage surgical protocol also frees healthcare resources to meet other needs, paving the way for a more cost-effective strategy for hospitals.

These attractive properties have resulted in more than 50,000 patients having been treated with CERAMENT and over 160 publications and abstracts, confirming safety and efficacy.