All open fractures are contaminated by exposure to the outside environment, and the more severe the soft tissue damage, the worse the clinical prognosis for infection, wound complications, non-union and amputation. The objectives of surgical treatment are to prevent infection, achieve union and restore function.
Fractures requiring open reduction internal fixation (ORIF) commonly have four main complications: non-union, re-fracture, implant failure and infection.
Deep infections cannot be cured in the presence of hardware, but removing hardware in the presence of an unhealed fracture greatly complicates management of the infection and the fracture.
In either open or ORIF cases, high-risk patients, such as those with diabetes and rheumatoid arthiritis, are at increased risk of wound complications, infection and failure of fixation.
CERAMENT remodels into bone within 6-12 months, reducing the risk of non-union or re-fracture, offers complete dead space management because it is both injectable and flowable, reducing the risk of infection; and can provide a high local concentration of antibiotic in CERAMENT| G and CERAMENT V, when needed.